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Hybrid alphavirus–rhabdovirus propagating replicon particles are versatile and potent vaccine vectors

Self-propagating, infectious, virus-like particles are generated in animal cell lines transfected with a Semliki Forest virus RNA replicon encoding a single viral structural protein, the vesicular stomatitis virus (VSV) glycoprotein. We show here that these infectious particles, which we call propag...

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Detalhes bibliográficos
Main Authors: Rose, Nina F., Publicover, Jean, Chattopadhyay, Anasuya, Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311333/
https://ncbi.nlm.nih.gov/pubmed/18391206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800280105
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