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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Expression of the regulatory subunit p85β of PI3K induces oncogenic transformation of primary avian fibroblasts. The transformed cells proliferate at an increased rate compared with nontransformed controls and show elevated levels of PI3K signaling. The oncogenic activity of p85β requires an active...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Ito, Yoshihiro, Hart, Jonathan R., Ueno, Lynn, Vogt, Peter K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250105/
https://ncbi.nlm.nih.gov/pubmed/25385636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420281111
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