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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Expression of the regulatory subunit p85β of PI3K induces oncogenic transformation of primary avian fibroblasts. The transformed cells proliferate at an increased rate compared with nontransformed controls and show elevated levels of PI3K signaling. The oncogenic activity of p85β requires an active...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Ito, Yoshihiro, Hart, Jonathan R., Ueno, Lynn, Vogt, Peter K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250105/
https://ncbi.nlm.nih.gov/pubmed/25385636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420281111
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