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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Expression of the regulatory subunit p85β of PI3K induces oncogenic transformation of primary avian fibroblasts. The transformed cells proliferate at an increased rate compared with nontransformed controls and show elevated levels of PI3K signaling. The oncogenic activity of p85β requires an active...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Ito, Yoshihiro, Hart, Jonathan R., Ueno, Lynn, Vogt, Peter K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250105/
https://ncbi.nlm.nih.gov/pubmed/25385636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420281111
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