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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)
Expression of the regulatory subunit p85β of PI3K induces oncogenic transformation of primary avian fibroblasts. The transformed cells proliferate at an increased rate compared with nontransformed controls and show elevated levels of PI3K signaling. The oncogenic activity of p85β requires an active...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250105/ https://ncbi.nlm.nih.gov/pubmed/25385636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420281111 |
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