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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)
Expression of the regulatory subunit p85β of PI3K induces oncogenic transformation of primary avian fibroblasts. The transformed cells proliferate at an increased rate compared with nontransformed controls and show elevated levels of PI3K signaling. The oncogenic activity of p85β requires an active...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250105/ https://ncbi.nlm.nih.gov/pubmed/25385636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420281111 |
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