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Isoform-specific activities of the regulatory subunits of phosphatidylinositol 3-kinases – potentially novel therapeutic targets
INTRODUCTION –: The main regulatory subunits of Class IA phosphatidylinositol 3-kinase (PI3K), p85α and p85β, initiate diverse cellular activities independent of binding to the catalytic subunit p110. Several of these signaling processes directly or indirectly contribute to a regulation of PI3K and...
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| Publicado en: | Expert Opin Ther Targets |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6197473/ https://ncbi.nlm.nih.gov/pubmed/30205700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2018.1522302 |
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