The Phosphatidylinositol 3-kinase Pathway as a Potential Therapeutic Target in Bladder Cancer

PURPOSE: Activation of the phosphatidylinositol 3-kinase (PI3K) pathway occurs in over 40% of bladder urothelial cancers. The aim of this study is to determine the therapeutic potential, the underlying action and resistant mechanisms of drugs targeting the PI3K pathway. EXPERIMENTAL DESIGN: Urotheli...

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Pubblicato in:Clin Cancer Res
Autori principali: Zeng, Shu-Xiong, Zhu, Yanjun, Ma, Ai-Hong, Yu, Weimin, Zhang, Hongyong, Lin, Tzu-Yin, Shi, Wei, Tepper, Clifford G., Henderson, Paul T., Airhart, Susan, Guo, Jian-Ming, Xu, Chuan-Liang, deVere White, Ralph W., Pan, Chong-Xian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668181/
https://ncbi.nlm.nih.gov/pubmed/28808038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0033
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