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Comparison of Intrapulmonary and Systemic Pharmacokinetics of Colistin Methanesulfonate (CMS) and Colistin after Aerosol Delivery and Intravenous Administration of CMS in Critically Ill Patients

Colistin is an old antibiotic that has recently gained a considerable renewal of interest for the treatment of pulmonary infections due to multidrug-resistant Gram-negative bacteria. Nebulization seems to be a promising form of administration, but colistin is administered as an inactive prodrug, col...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Antimicrob Agents Chemother
Κύριοι συγγραφείς: Boisson, Matthieu, Jacobs, Matthieu, Grégoire, Nicolas, Gobin, Patrice, Marchand, Sandrine, Couet, William, Mimoz, Olivier
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249558/
https://ncbi.nlm.nih.gov/pubmed/25267660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03510-14
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