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Aerosol Therapy with Colistin Methanesulfonate: a Biopharmaceutical Issue Illustrated in Rats
The aim of this study was to evaluate the biopharmaceutical behavior of colistin methanesulfonate (CMS) with special focus on colistin presystemic formation after CMS nebulization in rats. CMS was administered (15 mg·kg(−1) of body weight) either intravenously for systemic pharmacokinetic studies (n...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934989/ https://ncbi.nlm.nih.gov/pubmed/20547787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00411-10 |
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