Aerosol Therapy with Colistin Methanesulfonate: a Biopharmaceutical Issue Illustrated in Rats

The aim of this study was to evaluate the biopharmaceutical behavior of colistin methanesulfonate (CMS) with special focus on colistin presystemic formation after CMS nebulization in rats. CMS was administered (15 mg·kg(−1) of body weight) either intravenously for systemic pharmacokinetic studies (n...

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Библиографические подробности
Главные авторы: Marchand, Sandrine, Gobin, Patrice, Brillault, Julien, Baptista, Sara, Adier, Christophe, Olivier, Jean-Christophe, Mimoz, Olivier, Couet, William
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2010
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934989/
https://ncbi.nlm.nih.gov/pubmed/20547787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00411-10
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