Inhibitors of Nucleotidyltransferase Superfamily Enzymes Suppress Herpes Simplex Virus Replication

Herpesviruses are large double-stranded DNA viruses that cause serious human diseases. Herpesvirus DNA replication depends on multiple processes typically catalyzed by nucleotidyltransferase superfamily (NTS) enzymes. Therefore, we investigated whether inhibitors of NTS enzymes would suppress replic...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Tavis, John E., Wang, Hong, Tollefson, Ann E., Ying, Baoling, Korom, Maria, Cheng, Xiaohong, Cao, Feng, Davis, Katie L., Wold, William S. M., Morrison, Lynda A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249532/
https://ncbi.nlm.nih.gov/pubmed/25267681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03875-14
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