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Virus-Encoded B7-2 Costimulation Molecules Enhance the Protective Capacity of a Replication-Defective Herpes Simplex Virus Type 2 Vaccine in Immunocompetent Mice

Herpes simplex virus 2 (HSV-2) and, to a lesser extent, HSV-1 cause the majority of sexually transmitted genital ulcerative disease. No effective prophylactic vaccine is currently available. Replication-defective HSV stimulates immune responses in animals but produces no progeny virus, making it pot...

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Bibliografiset tiedot
Päätekijät: Vagvala, Sri P., Thebeau, Lydia G., Wilson, Saydra R., Morrison, Lynda A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612392/
https://ncbi.nlm.nih.gov/pubmed/18987142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02022-08
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