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Up to Four Distinct Polypeptides Are Produced from the γ34.5 Open Reading Frame of Herpes Simplex Virus 2

The herpes simplex virus 1 (HSV-1) ICP34.5 protein strongly influences neurovirulence and regulates several cellular antiviral responses. Despite the clinical importance of HSV-2, relatively little is known about its ICP34.5 ortholog. We found that HSV-2 produces up to four distinct forms of ICP34.5...

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Autors principals: Korom, Maria, Davis, Katie L., Morrison, Lynda A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178799/
https://ncbi.nlm.nih.gov/pubmed/25031346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01284-14
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