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Development of a Population Pharmacokinetic Model Characterizing the Tissue Distribution of Azithromycin in Healthy Subjects

Recent clinical trials indicate that the use of azithromycin is associated with the emergence of macrolide resistance. The objective of our study was to simultaneously characterize free target site concentrations and correlate them with the MIC(90)s of clinically relevant pathogens. Azithromycin (50...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Zheng, Songmao, Matzneller, Peter, Zeitlinger, Markus, Schmidt, Stephan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249372/
https://ncbi.nlm.nih.gov/pubmed/25155592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02904-14
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