Single- and Repeated-Dose Pharmacokinetics of Ceftaroline in Plasma and Soft Tissues of Healthy Volunteers for Two Different Dosing Regimens of Ceftaroline Fosamil

Ceftaroline fosamil (CPT-F) is currently approved for use for the treatment of complicated skin and soft tissue infections and community-acquired pneumonia at 600 mg twice daily (q12h), but other dosing regimens are under evaluation. To date, very limited data on the soft tissue pharmacokinetics (PK...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Matzneller, Peter, Lackner, Edith, Lagler, Heimo, Wulkersdorfer, Beatrix, Österreicher, Zoe, Zeitlinger, Markus
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879389/
https://ncbi.nlm.nih.gov/pubmed/27044549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00097-16
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