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Pharmacokinetics of Telithromycin in Plasma and Soft Tissues after Single-Dose Administration to Healthy Volunteers

By use of microdialysis we assessed the concentrations of telithromycin in muscle and adipose tissue to test its ability to penetrate soft tissues. The ratios of the area under the concentration-versus-time curve from 0 to 24 h to the MIC indicated that free concentrations of telithromycin in tissue...

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Détails bibliographiques
Auteurs principaux: Gattringer, Rainer, Urbauer, Eleonora, Traunmüller, Friederike, Zeitlinger, Markus, Dehghanyar, Pejman, Zeleny, Petra, Graninger, Wolfgang, Müller, Markus, Joukhadar, Christian
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC529224/
https://ncbi.nlm.nih.gov/pubmed/15561839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4650-4653.2004
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