Increase of Microcirculatory Blood Flow Enhances Penetration of Ciprofloxacin into Soft Tissue

The present study addressed the effect of microcirculatory blood flow on the ability of ciprofloxacin to penetrate soft tissues. Twelve healthy male volunteers were enrolled in an analyst-blinded, clinical pharmacokinetic study. A single intravenous dose of 200 mg of ciprofloxacin was administered o...

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Autores principales: Joukhadar, Christian, Dehghanyar, Pejman, Traunmüller, Friederike, Sauermann, Robert, Mayer-Helm, Bernhard, Georgopoulos, Apostolos, Müller, Markus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251507/
https://ncbi.nlm.nih.gov/pubmed/16189092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4149-4153.2005
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