Increase of Microcirculatory Blood Flow Enhances Penetration of Ciprofloxacin into Soft Tissue

The present study addressed the effect of microcirculatory blood flow on the ability of ciprofloxacin to penetrate soft tissues. Twelve healthy male volunteers were enrolled in an analyst-blinded, clinical pharmacokinetic study. A single intravenous dose of 200 mg of ciprofloxacin was administered o...

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Bibliografiska uppgifter
Huvudupphovsmän: Joukhadar, Christian, Dehghanyar, Pejman, Traunmüller, Friederike, Sauermann, Robert, Mayer-Helm, Bernhard, Georgopoulos, Apostolos, Müller, Markus
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251507/
https://ncbi.nlm.nih.gov/pubmed/16189092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4149-4153.2005
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