Relevance of Soft-Tissue Penetration by Levofloxacin for Target Site Bacterial Killing in Patients with Sepsis

Antimicrobial therapy of soft tissue infections in patients with sepsis sometimes lacks efficiency, despite the documented susceptibility of the causative pathogen to the administered antibiotic. In this context, impaired equilibration between the antibiotic concentrations in plasma and those in tis...

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Bibliographische Detailangaben
Hauptverfasser: Zeitlinger, M. A., Dehghanyar, P., Mayer, B. X., Schenk, B. S., Neckel, U., Heinz, G., Georgopoulos, A., Müller, M., Joukhadar, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC253769/
https://ncbi.nlm.nih.gov/pubmed/14576116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3548-3553.2003
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