Levofloxacin Population Pharmacokinetics and Creation of a Demographic Model for Prediction of Individual Drug Clearance in Patients with Serious Community-Acquired Infection

Population pharmacokinetic modeling is a useful approach to obtaining estimates of both population and individual pharmacokinetic parameter values. The potential for relating pharmacokinetic parameters to pharmacodynamic outcome variables, such as efficacy and toxicity, exists. A logistic regression...

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Detalhes bibliográficos
Main Authors: Preston, Sandra L., Drusano, George L., Berman, Adam L., Fowler, Cynthia L., Chow, Andrew T., Dornseif, Bruce, Reichl, Veronica, Natarajan, Jaya, Wong, Frankie A., Corrado, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105752/
https://ncbi.nlm.nih.gov/pubmed/9593134
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