Relevance of Soft-Tissue Penetration by Levofloxacin for Target Site Bacterial Killing in Patients with Sepsis

Antimicrobial therapy of soft tissue infections in patients with sepsis sometimes lacks efficiency, despite the documented susceptibility of the causative pathogen to the administered antibiotic. In this context, impaired equilibration between the antibiotic concentrations in plasma and those in tis...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Zeitlinger, M. A., Dehghanyar, P., Mayer, B. X., Schenk, B. S., Neckel, U., Heinz, G., Georgopoulos, A., Müller, M., Joukhadar, C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.11.3548-3553.2003
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