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Development of a Population Pharmacokinetic Model Characterizing the Tissue Distribution of Azithromycin in Healthy Subjects

Recent clinical trials indicate that the use of azithromycin is associated with the emergence of macrolide resistance. The objective of our study was to simultaneously characterize free target site concentrations and correlate them with the MIC(90)s of clinically relevant pathogens. Azithromycin (50...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Zheng, Songmao, Matzneller, Peter, Zeitlinger, Markus, Schmidt, Stephan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249372/
https://ncbi.nlm.nih.gov/pubmed/25155592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02904-14
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