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Development of a Population Pharmacokinetic Model Characterizing the Tissue Distribution of Azithromycin in Healthy Subjects

Recent clinical trials indicate that the use of azithromycin is associated with the emergence of macrolide resistance. The objective of our study was to simultaneously characterize free target site concentrations and correlate them with the MIC(90)s of clinically relevant pathogens. Azithromycin (50...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zheng, Songmao, Matzneller, Peter, Zeitlinger, Markus, Schmidt, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249372/
https://ncbi.nlm.nih.gov/pubmed/25155592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02904-14
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