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DnaJA1/Hsp40 Is Co-Opted by Influenza A Virus To Enhance Its Viral RNA Polymerase Activity

The RNA-dependent RNA polymerase (RdRp) of influenza A virus is a heterotrimeric complex composed of the PB1, PB2, and PA subunits. The interplay between host factors and the three subunits of the RdRp is critical to enable viral RNA synthesis to occur in the nuclei of infected cells. In this study,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Cao, Mengmeng, Wei, Candong, Zhao, Lili, Wang, Jingfeng, Jia, Qiannan, Wang, Xue, Jin, Qi, Deng, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249161/
https://ncbi.nlm.nih.gov/pubmed/25253355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02475-14
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