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Phosphorylation of Influenza A Virus NS1 at Serine 205 Mediates Its Viral Polymerase-Enhancing Function

Influenza A virus (IAV) nonstructural protein 1 (NS1) is a protein with multiple functions that are regulated by phosphorylation. Phosphoproteomic screening of H1N1 virus-infected cells revealed that NS1 was phosphorylated at serine 205 in intermediate stages of the viral life cycle. Interestingly,...

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Publicado en:J Virol
Autores principales: Patil, Amol, Anhlan, Darisuren, Ferrando, Verónica, Mecate-Zambrano, Angeles, Mellmann, Alexander, Wixler, Viktor, Boergeling, Yvonne, Ludwig, Stephan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094967/
https://ncbi.nlm.nih.gov/pubmed/33408177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02369-20
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