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DnaJA1/Hsp40 Is Co-Opted by Influenza A Virus To Enhance Its Viral RNA Polymerase Activity

The RNA-dependent RNA polymerase (RdRp) of influenza A virus is a heterotrimeric complex composed of the PB1, PB2, and PA subunits. The interplay between host factors and the three subunits of the RdRp is critical to enable viral RNA synthesis to occur in the nuclei of infected cells. In this study,...

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Publicat a:J Virol
Autors principals: Cao, Mengmeng, Wei, Candong, Zhao, Lili, Wang, Jingfeng, Jia, Qiannan, Wang, Xue, Jin, Qi, Deng, Tao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249161/
https://ncbi.nlm.nih.gov/pubmed/25253355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02475-14
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