HIV-1 Nef and Vpu Are Functionally Redundant Broad-Spectrum Modulators of Cell Surface Receptors, Including Tetraspanins

HIV-1 Nef and Vpu are thought to optimize virus replication in the infected host, at least in part via their ability to interfere with vesicular host cell trafficking. Despite the use of distinct molecular mechanisms, Nef and Vpu share specificity for some molecules such as CD4 and major histocompat...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Haller, Claudia, Müller, Birthe, Fritz, Joëlle V., Lamas-Murua, Miguel, Stolp, Bettina, Pujol, François M., Keppler, Oliver T., Fackler, Oliver T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249113/
https://ncbi.nlm.nih.gov/pubmed/25275127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02333-14
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