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Lentiviral Nef Proteins Utilize PAK2-Mediated Deregulation of Cofilin as a General Strategy To Interfere with Actin Remodeling

Nef is an accessory protein and pathogenicity factor of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) which elevates virus replication in vivo. We recently described for HIV type 1(SF2) (HIV-1(SF2)) the potent interference of Nef with T-lymphocyte chemotaxis via its asso...

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Detalhes bibliográficos
Main Authors: Stolp, Bettina, Abraham, Libin, Rudolph, Jochen M., Fackler, Oliver T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849517/
https://ncbi.nlm.nih.gov/pubmed/20147394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02467-09
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