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Lentiviral Nef Proteins Utilize PAK2-Mediated Deregulation of Cofilin as a General Strategy To Interfere with Actin Remodeling

Nef is an accessory protein and pathogenicity factor of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) which elevates virus replication in vivo. We recently described for HIV type 1(SF2) (HIV-1(SF2)) the potent interference of Nef with T-lymphocyte chemotaxis via its asso...

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Autori principali: Stolp, Bettina, Abraham, Libin, Rudolph, Jochen M., Fackler, Oliver T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849517/
https://ncbi.nlm.nih.gov/pubmed/20147394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02467-09
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