Inhibition of T-Cell Receptor-Induced Actin Remodeling and Relocalization of Lck Are Evolutionarily Conserved Activities of Lentiviral Nef Proteins

Nef, an important pathogenicity factor of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV), elevates virus replication in vivo. Among other activities, Nef affects T-cell receptor (TCR) signaling via several mechanisms. For HIV-1 Nef these include alteration of the organiza...

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Hlavní autoři: Rudolph, Jochen M., Eickel, Nina, Haller, Claudia, Schindler, Michael, Fackler, Oliver T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772722/
https://ncbi.nlm.nih.gov/pubmed/19726522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01423-09
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