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HIV-1 Nef and Vpu Are Functionally Redundant Broad-Spectrum Modulators of Cell Surface Receptors, Including Tetraspanins

HIV-1 Nef and Vpu are thought to optimize virus replication in the infected host, at least in part via their ability to interfere with vesicular host cell trafficking. Despite the use of distinct molecular mechanisms, Nef and Vpu share specificity for some molecules such as CD4 and major histocompat...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Haller, Claudia, Müller, Birthe, Fritz, Joëlle V., Lamas-Murua, Miguel, Stolp, Bettina, Pujol, François M., Keppler, Oliver T., Fackler, Oliver T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249113/
https://ncbi.nlm.nih.gov/pubmed/25275127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02333-14
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