Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats

BACKGROUND: High mobility group box-1 (HMGB1), a proinflammatory cytokine, plays a pivotal role in tissue remodeling and angiogenesis, both of which are crucial for the pathogenesis of pulmonary arterial hypertension. In this study, we explored the relationship between HMGB1 and pulmonary hypertensi...

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Bibliografski detalji
Izdano u:Respir Res
Glavni autori: Yang, Pil-Sung, Kim, Dae-Hoon, Lee, Yong Joon, Lee, Sang-Eun, Kang, Won Jun, Chang, Hyuk-Jae, Shin, Jeon-Soo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248446/
https://ncbi.nlm.nih.gov/pubmed/25420924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0148-4
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