Formononetin attenuates monocrotaline-induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats

Pulmonary arterial hypertension (PAH) is a life-threatening disease induced by the excessive proliferation and reduced apoptosis of pulmonary artery smooth muscle cells (PASMCs). Formononetin (FMN) is a natural isoflavone with numerous cardioprotective properties, which can inhibit the proliferation...

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Udgivet i:Mol Med Rep
Main Authors: Cai, Changhong, Xiang, Yijia, Wu, Yonghui, Zhu, Ning, Zhao, Huan, Xu, Jian, Lin, Wensheng, Zeng, Chunlai
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854580/
https://ncbi.nlm.nih.gov/pubmed/31702810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10781
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