Naringin Ameliorates Monocrotaline-Induced Pulmonary Arterial Hypertension Through Endothelial-To-Mesenchymal Transition Inhibition

Pulmonary arterial hypertension (PAH) caused by enhanced arterial pressure increases vessel resistance in the lung. Endothelial-to-mesenchymal transition (EndMT) plays key roles in the vascular remodeling in PAH. Naringin, a protective gaseous mediator is commonly extracted from tomatoes and citrus...

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Vydáno v:Front Pharmacol
Hlavní autoři: Wu, Yonghui, Cai, Changhong, Xiang, Yijia, Zhao, Huan, Lv, Lingchun, Zeng, Chunlai
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320371/
https://ncbi.nlm.nih.gov/pubmed/34335261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.696135
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