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HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors

BACKGROUND: Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are key players in epigenetic regulation of gene expression. Analgesic activity by HDAC inhibitors has been reported in different pain models including inflammatory and neuropathic pain. These drugs interfere with gene ex...

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Bibliografske podrobnosti
izdano v:Mol Pain
Main Authors: Zammataro, Magda, Sortino, Maria Angela, Parenti, Carmela, Gereau, Robert W, Chiechio, Santina
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247606/
https://ncbi.nlm.nih.gov/pubmed/25406541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-68
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