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HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors

BACKGROUND: Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are key players in epigenetic regulation of gene expression. Analgesic activity by HDAC inhibitors has been reported in different pain models including inflammatory and neuropathic pain. These drugs interfere with gene ex...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Zammataro, Magda, Sortino, Maria Angela, Parenti, Carmela, Gereau, Robert W, Chiechio, Santina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247606/
https://ncbi.nlm.nih.gov/pubmed/25406541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-68
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