HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors

BACKGROUND: Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are key players in epigenetic regulation of gene expression. Analgesic activity by HDAC inhibitors has been reported in different pain models including inflammatory and neuropathic pain. These drugs interfere with gene ex...

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Vydáno v:Mol Pain
Hlavní autoři: Zammataro, Magda, Sortino, Maria Angela, Parenti, Carmela, Gereau, Robert W, Chiechio, Santina
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247606/
https://ncbi.nlm.nih.gov/pubmed/25406541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-68
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