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Metabotropic glutamate receptors as targets for analgesia: antagonism, activation, and allosteric modulation

The metabotropic glutamate receptors (mGluRs) are expressed pre- and post-synaptically throughout the nervous system where they serve as modulators of synaptic transmission and neuronal excitability. Activation of mGluRs can be pro- or anti-nociceptive, depending on their anatomic location and the s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Montana, Michael C., Gereau, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678530/
https://ncbi.nlm.nih.gov/pubmed/21466446
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