Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We fine-mapped RA risk alleles within the major histocompatibility complex (MHC) in 2782 seropositive RA cases and 4315 controls of Asian descent....

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Publicat a:Hum Mol Genet
Autors principals: Okada, Yukinori, Kim, Kwangwoo, Han, Buhm, Pillai, Nisha E., Ong, Rick T.-H., Saw, Woei-Yuh, Luo, Ma, Jiang, Lei, Yin, Jian, Bang, So-Young, Lee, Hye-Soon, Brown, Matthew A., Bae, Sang-Cheol, Xu, Huji, Teo, Yik-Ying, de Bakker, Paul I.W., Raychaudhuri, Soumya
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Association Studies Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245039/
https://ncbi.nlm.nih.gov/pubmed/25070946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu387
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