Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We fine-mapped RA risk alleles within the major histocompatibility complex (MHC) in 2782 seropositive RA cases and 4315 controls of Asian descent....

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Vydáno v:Hum Mol Genet
Hlavní autoři: Okada, Yukinori, Kim, Kwangwoo, Han, Buhm, Pillai, Nisha E., Ong, Rick T.-H., Saw, Woei-Yuh, Luo, Ma, Jiang, Lei, Yin, Jian, Bang, So-Young, Lee, Hye-Soon, Brown, Matthew A., Bae, Sang-Cheol, Xu, Huji, Teo, Yik-Ying, de Bakker, Paul I.W., Raychaudhuri, Soumya
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Association Studies Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245039/
https://ncbi.nlm.nih.gov/pubmed/25070946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu387
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