Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We fine-mapped RA risk alleles within the major histocompatibility complex (MHC) in 2782 seropositive RA cases and 4315 controls of Asian descent....

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Okada, Yukinori, Kim, Kwangwoo, Han, Buhm, Pillai, Nisha E., Ong, Rick T.-H., Saw, Woei-Yuh, Luo, Ma, Jiang, Lei, Yin, Jian, Bang, So-Young, Lee, Hye-Soon, Brown, Matthew A., Bae, Sang-Cheol, Xu, Huji, Teo, Yik-Ying, de Bakker, Paul I.W., Raychaudhuri, Soumya
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Association Studies Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245039/
https://ncbi.nlm.nih.gov/pubmed/25070946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu387
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