Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We fine-mapped RA risk alleles within the major histocompatibility complex (MHC) in 2782 seropositive RA cases and 4315 controls of Asian descent....

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Okada, Yukinori, Kim, Kwangwoo, Han, Buhm, Pillai, Nisha E., Ong, Rick T.-H., Saw, Woei-Yuh, Luo, Ma, Jiang, Lei, Yin, Jian, Bang, So-Young, Lee, Hye-Soon, Brown, Matthew A., Bae, Sang-Cheol, Xu, Huji, Teo, Yik-Ying, de Bakker, Paul I.W., Raychaudhuri, Soumya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245039/
https://ncbi.nlm.nih.gov/pubmed/25070946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu387
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