Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We fine-mapped RA risk alleles within the major histocompatibility complex (MHC) in 2782 seropositive RA cases and 4315 controls of Asian descent....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Okada, Yukinori, Kim, Kwangwoo, Han, Buhm, Pillai, Nisha E., Ong, Rick T.-H., Saw, Woei-Yuh, Luo, Ma, Jiang, Lei, Yin, Jian, Bang, So-Young, Lee, Hye-Soon, Brown, Matthew A., Bae, Sang-Cheol, Xu, Huji, Teo, Yik-Ying, de Bakker, Paul I.W., Raychaudhuri, Soumya
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Association Studies Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245039/
https://ncbi.nlm.nih.gov/pubmed/25070946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu387
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