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Hydrogen–deuterium exchange in imidazole as a tool for studying histidine phosphorylation
Isotope exchange at the histidine C(2) atom of imidazole in D(2)O solution is well known to occur at a significantly slower rate than the exchange of amide protons. Analysis of the kinetics of this isotope-exchange reaction is proposed herein as a method of detecting histidine phosphorylation. This...
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| 出版年: | Anal Bioanal Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Berlin Heidelberg
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244536/ https://ncbi.nlm.nih.gov/pubmed/25354888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-014-8218-5 |
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