Chargement en cours...

Futsch/MAP1B mRNA Is a Translational Target of TDP-43 and Is Neuroprotective in a Drosophila Model of Amyotrophic Lateral Sclerosis

TDP-43 is an RNA-binding protein linked to amyotrophic lateral sclerosis (ALS) that is known to regulate the splicing, transport, and storage of specific mRNAs into stress granules. Although TDP-43 has been shown to interact with translation factors, its role in protein synthesis remains unclear, an...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Coyne, Alyssa N., Siddegowda, Bhavani Bagevalu, Estes, Patricia S., Johannesmeyer, Jeffrey, Kovalik, Tina, Daniel, Scott G., Pearson, Antony, Bowser, Robert, Zarnescu, Daniela C.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244467/
https://ncbi.nlm.nih.gov/pubmed/25429138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2526-14.2014
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!