Futsch/MAP1B mRNA Is a Translational Target of TDP-43 and Is Neuroprotective in a Drosophila Model of Amyotrophic Lateral Sclerosis

TDP-43 is an RNA-binding protein linked to amyotrophic lateral sclerosis (ALS) that is known to regulate the splicing, transport, and storage of specific mRNAs into stress granules. Although TDP-43 has been shown to interact with translation factors, its role in protein synthesis remains unclear, an...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Coyne, Alyssa N., Siddegowda, Bhavani Bagevalu, Estes, Patricia S., Johannesmeyer, Jeffrey, Kovalik, Tina, Daniel, Scott G., Pearson, Antony, Bowser, Robert, Zarnescu, Daniela C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244467/
https://ncbi.nlm.nih.gov/pubmed/25429138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2526-14.2014
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