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Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders
Choline acetyltransferase (ChAT) synthesizes acetylcholine in neurons and other cell types. Decreases in ChAT activity are associated with a number of disease states, and mutations in ChAT cause congenital neuromuscular disorders. The crystal structure of ChAT reported here shows the enzyme divided...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC424412/ https://ncbi.nlm.nih.gov/pubmed/15131697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600221 |
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