Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection

BACKGROUND: The inflammasome is an intracellular protein complex triggered by exposure to intracellular pathogens, its components or other endogenous proteins. It leads to the activation of and subsequent release of proinflammatory cytokines such as IL-1β and IL-18. S. Typhimurium is a Gram-negative...

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Dades bibliogràfiques
Publicat a:BMC Immunol
Autors principals: De Jong, Hanna K, Koh, Gavin CKW, van Lieshout, Miriam HP, Roelofs, Joris JTH, van Dissel, Jaap T, van der Poll, Tom, Wiersinga, W Joost
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243774/
https://ncbi.nlm.nih.gov/pubmed/25115174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0030-7
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