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Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection

BACKGROUND: The inflammasome is an intracellular protein complex triggered by exposure to intracellular pathogens, its components or other endogenous proteins. It leads to the activation of and subsequent release of proinflammatory cytokines such as IL-1β and IL-18. S. Typhimurium is a Gram-negative...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Immunol
Päätekijät: De Jong, Hanna K, Koh, Gavin CKW, van Lieshout, Miriam HP, Roelofs, Joris JTH, van Dissel, Jaap T, van der Poll, Tom, Wiersinga, W Joost
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243774/
https://ncbi.nlm.nih.gov/pubmed/25115174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0030-7
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