Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model

BACKGROUND: Typhoid fever, caused by the Gram-negative bacterium Salmonella enterica serovar Typhi, is a major cause of community-acquired bacteremia and death worldwide. S100A8 (MRP8) and S100A9 (MRP14) form bioactive antimicrobial heterodimers (calprotectin) that can activate Toll-like receptor 4,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Negl Trop Dis
Prif Awduron: De Jong, Hanna K., Achouiti, Ahmed, Koh, Gavin C. K. W., Parry, Christopher M., Baker, Stephen, Faiz, Mohammed Abul, van Dissel, Jaap T., Vollaard, Albert M., van Leeuwen, Ester M. M., Roelofs, Joris J. T. H., de Vos, Alex F., Roth, Johannes, van der Poll, Tom, Vogl, Thomas, Wiersinga, Willem Joost
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393299/
https://ncbi.nlm.nih.gov/pubmed/25860480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003663
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