Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model

BACKGROUND: Typhoid fever, caused by the Gram-negative bacterium Salmonella enterica serovar Typhi, is a major cause of community-acquired bacteremia and death worldwide. S100A8 (MRP8) and S100A9 (MRP14) form bioactive antimicrobial heterodimers (calprotectin) that can activate Toll-like receptor 4,...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: De Jong, Hanna K., Achouiti, Ahmed, Koh, Gavin C. K. W., Parry, Christopher M., Baker, Stephen, Faiz, Mohammed Abul, van Dissel, Jaap T., Vollaard, Albert M., van Leeuwen, Ester M. M., Roelofs, Joris J. T. H., de Vos, Alex F., Roth, Johannes, van der Poll, Tom, Vogl, Thomas, Wiersinga, Willem Joost
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393299/
https://ncbi.nlm.nih.gov/pubmed/25860480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003663
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