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Stargazin promotes closure of the AMPA receptor ligand-binding domain
Transmembrane AMPA receptor (AMPAR) regulatory proteins (TARPs) markedly enhance AMPAR function, altering ligand efficacy and receptor gating kinetics and thereby shaping the postsynaptic response. The structural mechanism underlying TARP effects on gating, however, is unknown. Here we find that the...
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| Gepubliceerd in: | J Gen Physiol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Rockefeller University Press
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242809/ https://ncbi.nlm.nih.gov/pubmed/25422502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411287 |
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