Stargazin promotes closure of the AMPA receptor ligand-binding domain

Transmembrane AMPA receptor (AMPAR) regulatory proteins (TARPs) markedly enhance AMPAR function, altering ligand efficacy and receptor gating kinetics and thereby shaping the postsynaptic response. The structural mechanism underlying TARP effects on gating, however, is unknown. Here we find that the...

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Bibliografiska uppgifter
I publikationen:J Gen Physiol
Huvudupphovsmän: MacLean, David M., Ramaswamy, Swarna S., Du, Mei, Howe, James R., Jayaraman, Vasanthi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2014
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242809/
https://ncbi.nlm.nih.gov/pubmed/25422502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411287
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