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A Membrane Proximal Helix in the Cytosolic Domain of the Human APP Interacting Protein LR11/SorLA Deforms Liposomes
Over the last decade, compelling evidence has linked the development of Alzheimer’s disease (AD) to defective intracellular trafficking of the amyloid precursor protein (APP). Faulty APP trafficking results in an overproduction of Aβ peptides, which is generally agreed to be the primary cause of AD-...
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| Опубликовано в: : | Biochim Biophys Acta |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242801/ https://ncbi.nlm.nih.gov/pubmed/24866012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.05.020 |
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